CORONARY FLOW - Disruptive AI Diagnostic Software
SEAMLESS WORKFLOW integration
How it works
STEP 1: CCTA acquisition
STEP 2: Biome results in PACS / workstation
STEP 3: Editable clinical report
What We Change
for the Patient
About Us
BIOME Science, founded in 2021, is developing CORONARY FLOW, the next generation AI diagnostic software transforming cardiac imaging using AI and physics, for the non-invasive assessment of coronary flow and stenoses.
BIOME improves clinical decision-making for the treatment of coronary heart disease.
Our Mission
BIOME Science is building the next generation of AI diagnostic software for coronary artery diseases in CCTA imaging, which enables cardiologists to determine whether a lesion truly causes ischemia. As a result, patients are not sent for unnecessary invasive procedures, while it is ensured that the severity of a lesion is sufficiently monitored.
Unique AI
architecture &
Patient-specific
Digital Twin
why we are different?
What we are working on
The Human & Systemic Problem
- Like cancer, CAD is a multifactor disease that current non-invasive tech fails to assess accurately
- Diagnostic uncertainty in intermediate lesions drives: → up to 60% of avoidable and sometimes dangerous invasive procedures → unnecessary stenting → procedural complications with increased healthcare costs → Poor and inefficient CAD screening and monitoring
- False positives lead to overtreatment. False negatives delay critical intervention. Physicians lack a reliable, fast, non-invasive tool for accurate patient CAD detection, decision and monitoring.
Why experts trust us
Biome developed a patented CCTA-driven FFR engine that merges data learning with physics through a unique AI architecture.
By combining computational fluid dynamics, experimental hemodynamic validation, and multi-factor clinical data, this hybrid model achieves around 93% accuracy compared to invasive wire-based FFR, offering physics-grade reliability at AI speed.
Biome's breakthrough lies in its unique AI architecture — trained on three complementary data streams that work in concert:
- Physics-based CFD simulations that capture the true mechanics of coronary blood flow
- Experimental hemodynamic data from rigorous in-vitro validation
- Real clinical imaging and multi-factor patient data that grounds every prediction in clinical reality
CORONARY FLOW AT A GLANCE
- High negative & positive predictive FFR values
- Visualizes plaque burden + vessel wall
- Accurate first-line test in stable chest pain
- Seamless integration in clinical workflows
Automatic upload at the end of acquisition
Cloud-based or On-Premise FFR-CT
Results pushed back automatically in PACS
min clinical report
% accuracy
research & partnership
Key clinical studies & publications
Voices of medical experts
Opinions of advisors & future clients
Glossary
Coronary flow glossary
